Cinnamic acids and derivatives
Aobchem N-(3 4-difluorophenyl)methoxycarboxamide | 95% | CAS 225385-91-1 | C8H7F2NO2 | 5g
N-(3 4-difluorophenyl)methoxycarboxamide | 95% | CAS 225385-91-1 | C8H7F2NO2 | 5g
Accela Chembio Inc 4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 5g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 5g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
Medchemexpress LLC HY-N0060 100mg Medchemexpress, Ferulic acid CAS:1135-24-6 Purity:>98%
Medchemexpress, HY-N0060 100mg Ferulic acid CAS:1135-24-6 Ferulic acid is a novel fibroblast growth factor receptor 1 ( FGFR1 ) inhibitor with IC 50 s of 3.78 and 12.5 μM for FGFR1 and FGFR2 , respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC p-Coumaric acid ethyl ester | 7362-39-2 | MFCD00210460 | 50 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase. It quenches the intrinsic fluorescence of the enzyme and changes the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain of tyrosinase, without binding to the copper ion of the enzyme. This compound is utilized in the development of medicines, cosmetics, and for fruit preservation.
- Non-competitive, reversible inhibitor of tyrosinase
- Quenches the intrinsic fluorescence of the enzyme
- Induces conformational changes in the catalytic domain of tyrosinase without binding to copper ion
- Exhibits anti-platelet activity in rabbit platelet-rich plasma
- Utilized in medicine and cosmetic development
- Used for fruit preservation
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 1 ML
p-Coumaric Acid Ethyl Ester, also known as Ethyl (E)-p-hydroxycinnamate or Ethyl trans-4-hydroxycinnamate, is a reversible, non-competitive inhibitor of tyrosinase. It quenches the enzyme's intrinsic fluorescence and alters the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain, without binding to the copper ion. This compound finds application in the development of various products, including medicines, cosmetics, and fruit preservation products that utilize pollen.
- Non-competitive and reversible tyrosinase inhibitor.
- Changes L-tyrosine binding affinity through conformational changes in tyrosinase's catalytic domain.
- Does not bind to the copper ion of the enzyme.
- Applicable in developing medicines.
- Used in cosmetic formulations.
- Utilized in fruit preservation products.
Apexbio Technology LLC Sodium ferulic 24276-84-4 500mg
Sodium ferulic (CAS 24276-84-4) is a small molecule inhibitor targeting fibroblast growth factor receptors specifically FGFR1 and FGFR2 It demonstrates inhibitory activity with IC50 values of 3 78 M for FGFR1 and 12 5 M for FGFR2 At the cellular level sodium ferulic suppresses intracellular signaling pathways involved in cell proliferation This compound is utilized in biomedical research to investigate signaling mechanisms and to assess therapeutic potential in disease models such as cancer
Apexbio Technology LLC BIBF 1202 894783-71-2 5mg
BIBF 1202 (CAS 894783-71-2) is a carboxylate metabolite derivative of BIBF 1120 characterized as a selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2) kinase In biochemical assays BIBF 1202 demonstrates inhibitory activity against VEGFR2 kinase with an IC50 of 62 nM This compound is frequently employed in studies investigating the regulation of the VEGFR2 signaling pathway and its role in endothelial cell function Additionally BIBF 1202 is utilized in preclinical models related to tumor angiogenesis and associated pharmacological research
Medchemexpress LLC 1-(2-dimethylaminoethyl)-1,2,3,4-tetrahydro-2-methylcarbazole hydrochloride | 54-84-2 | MFCD00055609 | 99.5% | 376.9 g/mol | C20H25ClN2OS | 1 ML
Cinanserin hydrochloride is the hydrochloride salt of cinanserin, supplied for research use as a 10 mM solution in DMSO (1 mL) and as solid quantities. It functions as a 5-HT2 receptor antagonist in pharmacological and biochemical studies and is provided with supporting documentation for quality control.
- Provided as 10 mM solution in DMSO (1 mL) and as solid pack sizes.
- High purity suitable for biochemical and pharmacological assays.
- Accompanied by a datasheet and certificate of analysis.
- Used as a 5-HT2 receptor antagonist in research applications.
- CAS number 54-84-2 for unambiguous chemical identification.
- Molecular weight 376.9 g/mol.
Cayman Chemical AMG 9810, Purity: ≥98%, CAS: 545395-94-6, 25 mg
A competitive antagonist of capsaicin activation of the TRPV1 (IC50s = 24.5 and 85.6 nM for human and rat, respectively); reverses thermal and mechanical hyperalgesia in a rat model of inflammatory pain
TARGETMOL CHEMICALS INC E/Z-DEMETHOXYCURCUMIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (p-Hydroxycinnamoyl)feruloylmethane is found in Curcuma zedoaria and Etlingera elatior. It has a role as a metabolite an antineoplastic agent and an anti-inflammatory agent. purity: 98%
Apexbio Technology LLC Tyrphostin AG 1296 146535-11-7 10mM (in 1mL DMSO)
Tyrphostin AG 1296 (CAS 146535-11-7) is a selective inhibitor of platelet-derived growth factor receptor (PDGFR) kinase via ATP-competitive binding Its inhibitory activity (IC50 0 3 0 5 M) results from inducing conformational changes in the ATP-binding domain of PDGFR blocking receptor autophosphorylation induced by ligand binding In vitro studies demonstrate inhibition of PDGF-stimulated mitogenesis (IC50 1 5 M) and cell proliferation (IC50 3 2 M) using Swiss 3T3 cells without significant effects on EGF receptor signaling at concentrations up to 100 M Tyrphostin AG 1296 serves as a research tool for investigating PDGFR-mediated signaling pathways
Sigma Aldrich Fine Chemicals Biosciences SB-366791 >=98% (HPLC), powder | 472981-92-3 | MFCD01033818 | 5MG
SB-366791 >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 287.74 | 472981-92-3 | MFCD01033818 | 5MG
Apexbio Technology LLC E-CINNAMAMIDE-1G
(E)-Cinnamamide (CAS No 22031-64-7) is a synthetic organic compound frequently used in biomedical research It originates from the naturally occurring cinnamic acid and is studied for its potential biological activities The compound acts through various molecular pathways and has been shown to interact with cellular targets impacting inflammatory and cancer pathways Commonly its in vitro activity is observed in the nanomolar to low micromolar range (E)-Cinnamamide is used in various research applications including drug screening assays cancer cell line studies and animal models to evaluate its therapeutic potential Experimental concentrations typically depend on the specific research design
Medchemexpress LLC Curcumin 5-8 | 890984-26-6 | 98.6% | 339.39 | 25 MG
Curcumin 5-8 (CUR5-8) is a potent and orally active naturally active curcumin (CUR) analog. It inhibits lipid droplet formation, increases autophagy, and inhibits apoptosis. Curcumin 5-8 also improves insulin resistance and insulin sensitivity. This product is for research use only and not sold to patients.
- Potent and orally active naturally active curcumin (CUR) analog.
- Inhibits lipid droplet formation.
- Increases autophagy.
- Inhibits apoptosis.
- Improves insulin resistance and insulin sensitivity.
- For research use only and not sold to patients.